I'm Dr Ash Otter, a microbiologist with experience across immunology and virology, specialising in understanding emerging viruses and vaccines.
Currently, I hold a Group Leader / PI position within the Emerging Pathogen Serology group at UK Health Security Agency (UKHSA).
My research spans a wide range pathogens but focusses on utilising serology and immunology tools for public health and translational potential. This includes from gaining our first fundamental understanding of the immunology of emerging pathogens, all the way through to using this knowledge to inform on new vaccine and diagnostic candidates.
I have extensive interests in all things microbial (not just viruses...), with particular interests across zoonoses, high-throughput testing, application of AI (LLMs, ML algorithms/training), and developing new methods to further elucidate pathogens.
P.s. Move the cursor around the antibodies
Leading a group of 13 staff, comprised of post-doctoral research associates, research scientists, and technicians. Expertise in the development, validation, and implementation of serology methods (ELISA, Luminex, MSD, LFDs etc) for a range of emerging pathogens, including for Mpox, Lassa, and Nipah.
Lead on submitting external funding applications to UKVN and UKRI with academic and industrial partners.
Leading on the implementation and evaluation of SARS-CoV-2 serology assays for use in serosurveillance and vaccine/research studies. Data used for national modelling and policy decision making (JCVI, DCMO).
Over 1.3 million tests conducted to date. Establishment of laboratory as new permanent group within UKHSA Porton (Emerging Pathogen Serology).
Involved in the development, evaluation, validation and implementation of new commercial and in-house diagnostic assays for diverse ACDP 2, 3 and 4 priority pathogens, including Arboviruses and viral haemorrhagiv fevers.
Part of RIPL 24/7 on-call team, supporting with PCR testing.
Thesis: "Understanding the role of Rv1255c, a TetR transcriptional regulator encoded in the RD13 region of Mycobacterium tuberculosis"
First-class honors. With industrial placement year.
Providing expertise within the the area of immunity and pathogenesis for ESCMID-related scientific affairs meetings and events.
Spearheading efforts to promote infection science within Microbiology Society community and bridging clinical and wet-lab research.
Contributing to assessment of managing and categorising vector-borne infections and risks within UK.
Technical expertise for serology for Mpox incident response and subseqeunt follow on studies.
Delivering lectures on diagnostics, immunology and emerging infections.
Providing strategic leadership within area of serology testing and sample management for UKHSA SIREN study.
Managing manuscript reviews and guiding editorial decisions, with a focus on virology, diagnostics, and emerging pathogens.
Aiding in decision making on serosurveillance projects and sample utilisation.
Teaching on subjects including emerging pathogens, diagnostics and vaccines.